ICAP connections are configured as a server-wide profile and scans are usually executed as a part of an event rule.
In addition to these, EFT should be able to communicate with any solution which uses the ICAP protocol. Pro2col have also tested Clearswift, which has AntiVirus and DLP capabilities built into a single solution.
If you are interested in finding out more about ICAP scanning with EFT, or would like support getting it up and running in your organisation, please get in touch.